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Andrew J Roe Selected Research

Anti-Bacterial Agents (Antibiotics)

1/2022Biosynthesis of Aurodox, a Type III Secretion System Inhibitor from Streptomyces goldiniensis.
10/2018Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis.
1/2018Postgenomics Characterization of an Essential Genetic Determinant of Mammary Pathogenic Escherichia coli.
8/2017Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition.

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Andrew J Roe Research Topics

Disease

11Infections
11/2023 - 02/2006
2Colorectal Neoplasms (Colorectal Cancer)
01/2024 - 03/2023
2Bacterial Infections (Bacterial Infection)
12/2021 - 08/2017
1Blister (Bulla)
11/2023
1Hemolytic-Uremic Syndrome
11/2023
1Chromosomal Instability (Chromosome Stability)
03/2023
1Meningitis
11/2022
1Coinfection
12/2021
1Critical Illness (Critically Ill)
12/2021
1COVID-19
12/2021
1Crohn Disease (Crohn's Disease)
01/2020
1Dysbiosis
10/2018
1Mastitis
01/2018
1Colitis
04/2017
1Dehydration (Water Stress)
04/2017
1Mitochondrial Diseases (Mitochondrial Disease)
11/2010
1Pyelonephritis
04/2006

Drug/Important Bio-Agent (IBA)

5Type III Secretion SystemsIBA
11/2023 - 01/2016
4Proteins (Proteins, Gene)FDA Link
11/2023 - 11/2010
4Anti-Bacterial Agents (Antibiotics)IBA
01/2022 - 08/2017
3Serine (L-Serine)FDA Link
03/2023 - 01/2016
2colibactinIBA
01/2024 - 03/2023
2Shiga Toxins (Vero Toxin)IBA
11/2023 - 04/2017
2AurodoxIBA
01/2022 - 01/2019
2Shiga Toxin (Shigella Toxin)IBA
01/2016 - 02/2006
1Biomarkers (Surrogate Marker)IBA
12/2021
1propionic acid (potassium propionate)IBA
01/2020
1IronIBA
01/2018
1ferric citrateIBA
01/2018
1Citric Acid (Citrate)FDA LinkGeneric
01/2018
1Cholera ToxinIBA
04/2017
1Caspase 3 (Caspase-3)IBA
01/2013
1Bacterial AdhesinsIBA
04/2006
1Virulence Factors (Pathogenicity Factors)IBA
02/2006

Therapy/Procedure

2Therapeutics
12/2021 - 01/2019
1Critical Care (Surgical Intensive Care)
12/2021